NLS-semiotica of IPA included nidal and interstitial hyperchromogenic changes, revealed most frequently at the early stages of the disease (1st – 4th day since the moment of clinical manifestations).

On 5th – 7th day we mainly registered foci and areas of alveolar infiltration, which evidenced progressing of the process. We should note subpleural localization of nidal and interstitial changes mainly, and revealed by Biophilia intruder-study connection of nidi and infiltration foci with vessels.

During the later period, starting from the 8th day since clinical manifestations, changes were polymorphous: we could see isochromogenic nidi, foci and infiltration areas, in rare cases – interstitial changes of pulmonary tissue. Only during the third period of IPA we registered air crescent symptom. Revealing of this symptom was a positive sign and it evidenced resolution of pathological changes.

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