Well-timed evaluation of changes in kidneys at acute pyelonephritis (AP) is still a pressing issue. Experience of nephrologists, urinologists and other clinicians, including experience in handling of visualizing diagnostics methods, does not always prevents severe clinical course of a disease with development of local purulent-destructive changes against the background of urosepsis down to lethal outcome. As majority of experts note, nothing, except clear and well-timed conclusion about serous or purulent-destructive stage of AP, can be a basis for choosing between conservative or surgical tactics in case management. However, in practice clinicians in majority of cases have no reliable and safe methods to reveal renal changes at various forms of AP and identify speed of their development and spreading. Existing diagnostic methods, such as x-ray, radioisotope scanning, thermography in majority of cases are inapplicable for highly informative and dynamic evaluation of extraperitoneal structures at AP. The reasons were complexity and expensiveness of these methods with, at the same time, subjectiveness of acquired data evaluation or impossibility to apply them due to needs in limitations to radiation exposure.

We believe that medical references have insufficient amount of works on application of Bioplasm NLS study in diagnostics of urorenal pathologies. Only few studies on evaluation of organic renal changes, including nidal manifestations at acute and chronic inflammatory processes were published. However they give no clear methods for revealing and interpretation of renal changes at AP in relation to morphogenesis stages of this disease, leaving open a question about accuracy of Bioplasm NLS-graphy data. Thus a problem of well-timed differentiation of local serous and purulent-destructive changes at AP is still unsolved for therapists and Bioplasm NLS-specialists.

The objective of this work is to evaluate Bioplasm NLS-graphic manifestation of so-called dynamic morphological stereotype of studied disease, in other words – to show Bioplasm NLS-semiotics of AP.