According to OMERACT there are no difference between cysts and erosions, and destruction degree is measured in points from 1 to 6. In a work of A.U. Vassiliev cysts and erosions are studied separately, but in our study we preferred to use international method of evaluation OMERACT–RAMRIS.

Higher diagnostic possibilities of Bioplasm  in revealing of bone tissue destruction are defined by physical parameters of this method. Differing from roentgenography, where the basis of the method is absorption of x-ray radiation by osseous tissue, application of non-linear scanning method is based on evaluation of background information noise released by destructing biological structure. That is why Bioplasm diagnostic method allows to evaluate the earliest pre-clinical changes in organs and tissues, which is impossible to do using other hardware methods of investigations (x-ray, ultrasound, CT, MRI), that can detect already formed, “perceptible to the eye” pathological process.