RESULTS AND DISCUSSION

1. Ultramicro-Metatron 4025 hunter-semiotics of urinary bladder tumors. Difficulties of Metatron 4025 hunter--diagnostics of urinary bladder tumors

We have developed ultramicro-Metatron 4025 hunter--semiotics of healthy urinary bladder wall and urinary bladder wall with tumoral affection. Healthy urinary bladder wall has 2.5-8.0 mm. in thickness (depending on its filling). In majority of cases it is possible to visualize 3 layers of bladder wall:

1) inner layer corresponds to mucous membrane with submucous layer; in its normal state – moderate hypochromogenic (2-3 points according to Fleindler’s scale);

2) middle layer corresponds to muscular layer; in its normal state – hypochromogenic (2 points according to Fleindler’s scale);

3) outer layer corresponds to adventitious membrane; in its normal state – a-hypochromogenic (1-2 points according to Fleindler’s scale);

Most commonly urinary bladder cancer in Metatron 4025 hunter--microscopic image has an appearance of exophytic formation of high hyperchromogenecy (5-6 points according to Fleindler’s scale) of round or irregular-shape with uneven surface. In case of absence of infiltrating growth the line between tumor bottom and urinary bladder wall is sharply defined, even and hypochromogenic (1-2 points). In case of infiltration the line between tumor bottom and urinary bladder wall firstly becomes uneven, obscure then there appear tumor structures in the wall’s depth. In this case wall layers stop differentiating. If the tumor grows into the whole wall’s depth then the outer contour of the wall becomes uneven, sometimes obscure.